Clinical Expertise

Dr Mackintosh provides assessment and ongoing management of interstitial lung disease (ILD) and related conditions for patients across Brisbane and Queensland.

Interstitial lung disease & pulmonary fibrosis

Interstitial Lung Disease

A broad group of conditions causing scarring or inflammation of the lung tissue. Dr Mackintosh co-chairs the Queensland Statewide ILD Multidisciplinary Meeting.

Interstitial lung disease

Idiopathic Pulmonary Fibrosis

A progressive fibrotic lung disease of unknown cause. Dr Mackintosh is first author of the current Australian and New Zealand treatment guideline for IPF.

Idiopathic pulmonary fibrosis

Progressive Pulmonary Fibrosis

A pattern of worsening fibrosis over time, occurring in IPF or other fibrotic ILDs. Dr Mackintosh is first author of Australia and New Zealand's PPF treatment guideline.

Progressive pulmonary fibrosis

Connective Tissue Disease (CTD-ILD)

Interstitial lung disease occurring alongside conditions such as systemic sclerosis, rheumatoid arthritis and inflammatory myopathies, managed jointly with rheumatology.

Connective tissue disease-associated ILD

Hypersensitivity Pneumonitis

ILD triggered by inhaled environmental or occupational antigens, requiring identification and avoidance of the trigger where possible.

Hypersensitivity pneumonitis

Asbestosis

Pulmonary fibrosis caused by occupational asbestos exposure, an important cause of ILD in Queensland given its industrial history.

Asbestosis

Sarcoidosis

A granulomatous condition most often affecting the lungs and chest lymph nodes, including complex and fibrotic pulmonary disease.

Sarcoidosis

Genetics & familial disease

Familial Interstitial Lung Disease

Pulmonary fibrosis occurring in two or more blood relatives, often linked to inherited gene variants. Dr Mackintosh founded and chairs the Australasian ILD Genetics Multidisciplinary Meeting.

Familial interstitial lung disease

Telomere Biology Disorders

Short telomere syndromes that can present with pulmonary fibrosis. Dr Mackintosh led the first international consensus statement on this topic for the ISHLT.

Telomere biology disorders

Genetics

Genetic evaluation for pulmonary fibrosis and ILD, including testing for telomere-related and surfactant-related genes and genetic counselling.

Genetics in ILD

Lung transplantation

Lung Transplantation

As a physician with the Queensland Lung Transplant Service at The Prince Charles Hospital, Dr Mackintosh assesses patients with advanced or progressive lung disease for suitability for lung transplantation, including patients with telomere biology disorders, where pre- and post-transplant management requires specific consideration.

Lung transplantation

Clinical trials

ILD & Pulmonary Fibrosis Clinical Trials

Dr Mackintosh is Principal Investigator on a number of Phase 1–3 ILD clinical trials and sits on the Steering Committee of PACT, the national pulmonary fibrosis trials network. Find out what taking part involves, and search for a trial in Queensland.

ILD clinical trials

For referring clinicians

Referrals are welcome from GPs, rheumatologists and other specialists.